Dedee Pfeiffer (born January 1, 1964) is an American film and television actress.
Pfeiffer was born Dorothy D. Pfeiffer in Midway City, California, the daughter of Donna (nee Taverna), a home-maker, and Richard Pfeiffer, a heating and air-conditioning contractor. She is the sister of actresses Michelle Pfeiffer and Lori Pfeiffer.
Pfeiffer has starred in many films and on TV. One of her best-known TV roles is on Cybill Shepherd's television series Cybill, as her daughter, "Rachel Blanders," from 1995-1997. She also starred in the TV series For Your Love from 1998 to 2002. She starred with Susanna Hoffs in the 1987 film The Allnighter and has made guest appearances on the TV shows Simon & Simon, Ellen, Seinfeld, Friends, Dream On, CSI: Crime Scene Investigation and The Dead Zone among others.
Pfeiffer also posed nude for Playboy magazine's February 2002 edition.